Health and sustainability outcomes of vegetarian dietary patterns: a revisit of the EPIC-Oxford and the Adventist Health Study-2 cohorts (2024)

  • Ruby MB, Heine SJ, Kamble S, Cheng TK, Waddar M. Compassion and contamination. Cult Differ Veg Appetite. 2013;71:340–8.

    Google Scholar

  • Leitzmann C. Vegetarian nutrition: past, present, future. Am J Clin Nutr. 2014;100:496S–502S.

    Article CAS Google Scholar

  • Vegetarian Resource Group. Poll information [Internet]. How many adults in the U.S. are vegetarian and vegan? How many adults eat vegetarian and vegan meals when eating out? 2017. http://www.vrg.org/nutshell/Polls/2016_adults_veg.htm. Accessed 12 April 2017.

  • Vegetarian Society of the United Kingdom. Veggie living fact sheets [Internet]. Statistics: number of UK vegetarians. 2012. https://www.vegsoc.org/sslpage.aspx?pid=753.

  • Melina V, Craig W, Levin S. Position of the academy of nutrition and dietetics: vegetarian diets. J Acad Nutr Diet. 2016;116:1970–80.

    Article Google Scholar

  • Beeson WL, Mills PK, Phillips RL, Andress M, Fraser GE. Chronic disease among seventh-day adventists, a low-risk group - rationale, methodology, and description of the population. Cancer. 1989;64:570–81.

    Article CAS Google Scholar

  • Appleby PN, Thorogood M, Mann JI, Key TJ. The Oxford vegetarian study: an overview. Am J Clin Nutr. 1999;70(3 Suppl):525S–531S.

    Article CAS Google Scholar

  • Davey GK, Spencer EA, Appleby PN, Allen NE, Knox KH, Key TJ. EPIC-Oxford: lifestyle characteristics and nutrient intakes in a cohort of 33,883 meat-eaters and 31,546 non meat-eaters in the UK. Public Health Nutr. 2003;6:259–68.

    Article Google Scholar

  • Butler TL, Fraser GE, Beeson WL, et al. Cohort profile: the Adventist Health Study-2 (AHS-2). Int J Epidemiol. 2008;37:260–5.

    Article Google Scholar

  • Jaceldo-Siegl K, Knutsen SF, Sabate J, et al. Validation of nutrient intake using an FFQ and repeated 24 h recalls in black and white subjects of the Adventist Health Study-2 (AHS-2). Public Health Nutr. 2010;13:812–9.

    Article Google Scholar

  • Appleby PN, Crowe FL, Bradbury KE, Travis RC, Key TJ. Mortality in vegetarians and comparable nonvegetarians in the United Kingdom. Am J Clin Nutr. 2016;103:218–30.

    Article CAS Google Scholar

  • Schmidt JA, Crowe FL, Appleby PN, Key TJ, Travis RC. Serum uric acid concentrations in meat eaters, fish eaters, vegetarians and vegans: a cross-sectional analysis in the EPIC-Oxford cohort. PLoS ONE. 2013;8:e56339.

    Article CAS Google Scholar

  • Orlich MJ, Jaceldo-Siegl K, Sabate J, Fan J, Singh PN, Fraser GE. Patterns of food consumption among vegetarians and non-vegetarians. Br J Nutr. 2014;112:1644–53.

    Article CAS Google Scholar

  • Burkholder-Cooley N, Rajaram S, Haddad E, Fraser GE, Jaceldo-Siegl K. Comparison of polyphenol intakes according to distinct dietary patterns and food sources in the Adventist Health Study-2 cohort. Br J Nutr. 2016;115:2162–9.

    Article CAS Google Scholar

  • Jaceldo-Siegl K, Lutjohann D, Sirirat R, Mashchak A, Fraser GE, Haddad E. Variations in dietary intake and plasma concentrations of plant sterols across plant-based diets among North American adults. Mol Nutr Food Res. 2017. https://doi.org/10.1002/mnfr.201600828

    Article Google Scholar

  • Klingberg S, Andersson H, Mulligan A, et al. Food sources of plant sterols in the EPIC Norfolk population. Eur J Clin Nutr. 2008;62:695–703.

    Article CAS Google Scholar

  • Sobiecki JG, Appleby PN, Bradbury KE, Key TJ. High compliance with dietary recommendations in a cohort of meat eaters, fish eaters, vegetarians, and vegans: results from the European Prospective Investigation into Cancer and Nutrition-Oxford study. Nutr Res. 2016;36:464–77.

    Article CAS Google Scholar

  • Schmidt JA, Rinaldi S, Scalbert A, et al. Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: a cross-sectional analysis in the EPIC-Oxford cohort. Eur J Clin Nutr. 2016;70:306–12.

    Article CAS Google Scholar

  • Rizzo NS, Jaceldo-Siegl K, Sabate J, Fraser GE. Nutrient profiles of vegetarian and non-vegetarian dietary patterns. J Acad Nutr Diet. 2013;113:1610–9.

    Article Google Scholar

  • Key TJ, Appleby PN, Crowe FL, Bradbury KE, Schmidt JA, Travis RC. Cancer in British vegetarians: updated analyses of 4998 incident cancers in a cohort of 32,491 meat eaters, 8612 fish eaters, 18,298 vegetarians, and 2246 vegans. Am J Clin Nutr. 2014;100:378S–385S.

    Article CAS Google Scholar

  • Orlich MJ, Singh PN, Sabate J, et al. Vegetarian dietary patterns and mortality in Adventist Health Study 2. JAMA Intern Med. 2013;173:1230–8.

    Article CAS Google Scholar

  • Orlich MJ, Fraser GE. Vegetarian diets in the Adventist Health Study 2: a review of initial published findings. Am J Clin Nutr. 2014;100:353S–358S.

    Article CAS Google Scholar

  • Tantamango-Bartley Y, Jaceldo-Siegl K, Fan J, Fraser G. Vegetarian diets and the incidence of cancer in a low-risk population. Cancer Epidemiol Biomark Prev. 2013;22:286–94.

    Article Google Scholar

  • Orlich MJ, Singh PN, Sabate J, Fan J, Sveen L, Bennett H, et al. Vegetarian dietary patterns and the risk of colorectal cancers. JAMA Intern Med. 2015;175:767–76.

    Article Google Scholar

  • Spencer EA, Appleby PN, Davey GK, Key TJ. Diet and body mass index in 38,000 EPIC-Oxford meat-eaters, fish-eaters, vegetarians and vegans. Int J Obes. 2003;27:728–34.

    Article CAS Google Scholar

  • Appleby PN, Davey GK, Key TJ. Hypertension and blood pressure among meat eaters, fish eaters, vegetarians and vegans in EPIC-Oxford. Public Health Nutr. 2002;5:645–54.

    Article Google Scholar

  • Key TJ, Appleby PN, Spencer EA, Travis RC, Roddam AW, Allen NE. Mortality in British vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford). Am J Clin Nutr. 2009;89:1613S–1619S.

    Article CAS Google Scholar

  • Pettersen BJ, Anousheh R, Fan J, Jaceldo-Siegl K, Fraser GE. Vegetarian diets and blood pressure among White subjects: results from the Adventist Health Study-2 (AHS-2). Public Health Nutr. 2012;15:1909–16.

    Article Google Scholar

  • Tonstad S, Butler T, Yan R, Fraser GE. Type of vegetarian diet, body weight, and prevalence of type 2 diabetes. Diabetes Care. 2009;32:791–6.

    Article Google Scholar

  • Tonstad S, Stewart K, Oda K, Batech M, Herring RP, Fraser GE. Vegetarian diets and incidence of diabetes in the Adventist Health Study-2. Nutr Metab Cardiovasc Dis. 2013;23:292–9.

    Article CAS Google Scholar

  • Rizzo NS, Sabate J, Jaceldo-Siegl K, Fraser GE. Vegetarian dietary patterns are associated with a lower risk of metabolic syndrome: the Adventist Health Study 2. Diabetes Care. 2011;34:1225–7.

    Article Google Scholar

  • Crowe FL, Appleby PN, Allen NE, Key TJ. Diet and risk of diverticular disease in Oxford cohort of European Prospective Investigation into Cancer and Nutrition (EPIC): prospective study of British vegetarians and non-vegetarians. Br Med J. 2011;343:d4131.

    Article Google Scholar

  • Le LT, Sabate J. Beyond meatless, the health effects of vegan diets: findings from the Adventist cohorts. Nutrients. 2014;6:2131–47.

    Article Google Scholar

  • Sabate J, Wien M. Vegetarian diets and childhood obesity prevention. Am J Clin Nutr. 2010;91:1525S–1529S.

    Article Google Scholar

  • Appleby PN, Key TJ. The long-term health of vegetarians and vegans. P Nutr Soc. 2016;75:287–93.

    Article Google Scholar

  • Palli D. InterAct consortium. Association between dietary meat consumption and incident type 2 diabetes: the EPIC-InterAct study. Diabetologia. 2013;56:47–59.

    Article Google Scholar

  • Burlingame B, Dernini S. Sustainable diets and biodiversity: directions and solutions for policy, research and action. Proceedings of the International Scientific Symposium, Biodiversity and Sustainable Diets United Against Hunger. Rome, Italy: FAO Headquarters; 2010. p. 83.

  • Sabate J, Soret S. Sustainability of plant-based diets: back to the future. Am J Clin Nutr. 2014;100:476S–482S.

    Article CAS Google Scholar

  • Sabate J, Sranacharoenpong K, Harwatt H, Wien M, Soret S. The environmental cost of protein food choices. Public Health Nutr. 2014;18:2067–73. https://doi.org/10.1017/S1368980014002377.

    Article PubMed Google Scholar

  • Marlow HJ, Harwatt H, Soret S, Sabate J. Comparing the water, energy, pesticide and fertilizer usage for the production of foods consumed by different dietary types in California. Public Health Nutr. 2015;18:2425–32.

    Article Google Scholar

  • Soret S, Mejia A, Batech M, Jaceldo-Siegl K, Harwatt H, Sabate J. Climate change mitigation and health effects of varied dietary patterns in real-life settings throughout North America. Am J Clin Nutr. 2014;100:490S–495S.

    Article CAS Google Scholar

  • Scarborough P, Appleby PN, Mizdrak A, et al. Dietary greenhouse gas emissions of meat-eaters, fish-eaters, vegetarians and vegans in the UK. Clim Change. 2014;125:179–92.

    Article CAS Google Scholar

  • Dietary Guidelines Advisory Committee. Scientific report of the 2015 dietary guidelines advisory committee, Vol 7. Washington, DC: US Departments of Agriculture and Health and Human Services; 2015. p. 202–4.

  • Nelson ME, Hamm MW, Hu FB, Abrams SA, Griffin TS. Alignment of healthy dietary patterns and environmental sustainability: a systematic review. Adv Nutr. 2016;7:1005–25.

    Article Google Scholar

  • Reynolds CJ, Buckley JD, Weinstein P, Boland J. Are the dietary guidelines for meat, fat, fruit and vegetable consumption appropriate for environmental sustainability? A review of the literature. Nutrients. 2014;6:2251–65.

    Article Google Scholar

  • US Census Bureau. International Data Base. Total midyear population for the world: 1950–2050. https://www.census.gov/population/international/data/idb/worldpoptotal.php. Accessed 11th April, 2018.

  • Bellavia A, Stilling F, Wolk A. High red meat intake and all-cause cardiovascular and cancer mortality: is the risk modified by fruit and vegetable intake? Am J Clin Nutr. 2016;104:1137–43.

    Article CAS Google Scholar

  • American Institute for Cancer Research; World Cancer Research Fund. Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington, D.C.: AICR; 2007.

  • Sinha R, Cross AJ, Graubard BI, Leitzmann MF, Schatzkin A. Meat intake and mortality: a prospective study of over half a million people. Arch Intern Med. 2009;169:562–71.

    Article CAS Google Scholar

  • Health and sustainability outcomes of vegetarian dietary patterns: a revisit of the EPIC-Oxford and the Adventist Health Study-2 cohorts (2024)
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